Read ISOPT’s publication on the Global Cancer Crisis.
Explore our review on the increasing burden, deepening inequality and effective prevention initiatives.
Explore our review on the increasing burden, deepening inequality and effective prevention initiatives.
Welcome to the ISOPT Virtual Meetings and Videos hub, where innovation meets accessibility in cancer research. Here, you can explore a collection of informative sessions and expert-led discussions that delve into the latest advancements and findings in cancer care. Our virtual meeting platform facilitates collaboration and knowledge sharing, making it easier than ever for professionals and researchers worldwide to engage with cutting-edge information. Join us as we connect, learn, and contribute to the fight against cancer together.
Breast cancer is one of the best models showing how neoadjuvant therapy in defined molecular phenotypes leads to de-escalation of surgery and radiation therapies, and better selection of treatment after surgery, including switching to a second line systemic therapy when patients don’t have a complete or near complete response to the first line neoadjuvant therapy.
7 months ago
HOPE RUGO
A simple collection of a woman’s tears has been shown to detect early breast cancer and can be used as a biomarker to in high-risk women or for surveillance of recurrence after breast cancer treatment.
7 months ago
SUZANNE KLIMBERG
The video discusses prevention strategies, screening guidelines and treatment options for both primary and metastatic cancer of the uterine cervix. Since 90% of cervical cancers are related to HPV virus infection, an HPV cancer vaccine can prevent most types of cervical cancer if administered in younger age women.
7 months ago
DOMENICA LORUSSO
The NCCN guidelines for screening and diagnosis of breast cancer are used worldwide and available in multiple languages. The video discusses the current screening techniques for breast cancer, including age of screening onset, screening frequency, types of imaging techniques, supplemental screening in high-risk women, and recommendations in resource- constrained countries. Guidelines details can be accessed free at www.nccn.org. after registration.
7 months ago
THERESE BEVERS
Adenocarcinoma od the lung in non-smokers is rising in incidence globally, especially in Asia. Large population-based screening has yielded occult lung cancer in 1.5 to 2.5% of high-risk individuals (96% were stage 0 or 1. Criteria for prevention, risk assessment and screening are discussed.
7 months ago
TONY MOK
The types of screening tests are discussed for detection of early colorectal cancer using fecal tests and blood tests. Colonoscopy remains the gold standard for detection of precancerous lesions and early colorectal cancer. Individuals at increased risk for colon cancer who should be considered for prevention intervention, including those with multiple colorectal polyps, inflammatory bowel disease, and those who have inherited genetic risk, the Lynch Syndrome (hereditary nonpolyposis colorectal cancer).
7 months ago
PATRICK LYNCH
Esophagogastric cancer had different histology and natural history in different geographic regions, and strategies for prevention and treatment are tailored to the histology and previous history of GI disorders. Asian countries with widespread screening have survival rates double that of countries without population screening. Individuals with ALDH2-deficient genotypes have increased risk for esophageal cancers from drinking alcohol. Minimally invasive surgical techniques are discussed.
7 months ago
YUKO KITAGAWA
Obesity is a major risk factor for 13 cancers, especially colorectal cancer (CRC) and has surpassed the cancer risk of tobacco. CRC is increasing in younger individuals under 45 years of age. There is a multitude of biological mechanisms linking energy balance and obesity as a driver for cancer, also to survival. The gut microbiome is also associated with survival in early-stage CRC.
7 months ago
CORNELIA ULRICH
Gastroesophageal and colorectal cancers are a major life-threatening disease and often present at advanced stages. Discussions about selecting high-immunogenecity subtypes (such as MSI hi; high TMB) to optimize chemoimmunotherapy combinations and facilitate organ-sparing operations, and to propose new strategies for improving immunotherapy efficiency in GI cancers by reversing immunotherapy resistance with drugs that induce immunogenic tumor cell death and to modulate the immune microenvironment.
7 months ago
RUIHUA XU
Screening should be considered for individuals with inherited pancreatic cancer predisposition, including those with a strong family history, high-grade intraductal papillary mucinous neoplasm (IPMN), or known genetic syndromes such as Peutz-Jeghers syndrome or hereditary pancreatitis. Particular attention should be given to individuals harboring germline pathogenic variants in genes such as BRCA1/2, PALB2, ATM, or mismatch repair genes associated with Lynch syndrome. Early detection through routine screening in these high-risk individuals has been associated with significantly improved outcomes. For select high-risk patients, prophylactic organ-preserving pancreatic surgery can be safely performed to reduce cancer incidence. A video demonstration of robotic pancreatectomy for this indication is included.
7 months ago
JIE HE
The incidence and mortality of nasopharyngeal cancer (NPC) is declining in Hong Kong. Multiple approaches are described, including identifying ingested salted fish with nitrosamines and smoking as causative agents, NPC genetic susceptibility, and use of HPV vaccine. Treatment advances are discussed using combinations of radiation therapy and chemotherapy and recent use of immunotherapy.
8 months ago
ANNE LEE
Epstein-Barr virus (EBV) is a known cause of nasopharyngeal carcinoma (NPC) which is endemic in Asia and parts of Africa. Anti-viral vaccines are effective in preventing NPC and detection of the EBV biomarkers in blood or nasal secretions can be an important screening tool for NPC, and for monitoring for relapse. accessed free at www.nccn.org. after registration.
7 months ago
VICTOR HF LEE
Genetic testing for inherited (germline) mutation and pathological variants have become technically and economically feasible. Most cancer patients with possible inherited contribution should undergo germline testing, especially those with breast, ovary, and colorectal cancers. This information ,plus family history, lifestyle, age and gender can be used to make informed for personalized risk stratification in individuals and family members. Population-based genetic screening can identify individuals at risk for future cancer development (often at an earlier age) and can benefit from prevention intervention or screening.
7 months ago
JEFFREY WEITZEL
Guidelines developed by oncology experts at the National Comprehensive Cancer Network (NCCN) have been used worldwide for all cancers, including specific situation in all stages of cancer, and guidelines for screening and prevention. Dr Gradishar, Chair of the NCCN Breast Guidelines Committee reviews guidelines for major cancers, including lung, prostate and colorectal cancer.
8 months ago
WILLIAM GRADISHAR
The “European Beating Cancer Plan” is described with the goal of increasing participation in all European countries with standardized cancer prevention and screening guidelines to reduce the cancer burden. These include tobacco cessation, use of cancer anti-viral vaccines, and screening for breast, uterine cervix, lung, and colorectal cancer. A European Cancer Inequalities Registry shows performance and adherence for each European country at https://cancer-inequalities.jic.ec.europa.eu.
7 months ago
ISABEL RUBIO
The Singapore Health System has initiated a “National Health Screening Program “Screen for Life” with screening recommendations based on age and gender, and pre-existing conditions for cervical breast and colorectal cancers. Although the incidence of cancer has increased the proportion of patients presenting with advanced cancer has significantly decreased. They have instituted a series of biomarker and radiological screening studies for gastric, colorectal and lung cancer.
7 months ago
SOON THYE LIM
The highest incidence of skin cancer, including melanoma occurs among fair-skinned population in Australia, New Zealand and the United States. Government sponsored nationwide educational programs have been instituted in Australia which now sees a decrease in melanoma incidence. Tanning beds and salons are also associated with melanoma and are attributed as the primary cause of melanoma in young adults. Government policies have banned tanning beds in Australia altogether and an increasing number of states in the USA have prohibited use of tanning beds for those under 18 years of age. The government of Poland now uses this as a model policy in their country.
7 months ago
JEFFREY GERSHENWALD AND JOHN THOMPSON
This video discusses the Latin American Cancer Code, which is based on The World Code Against Cancer Framework (https://cancer-code-world.iarc.who.int). Developed by 60 experts from across Latin America, this comprehensive document adapts global cancer prevention strategies for regional implementation, targeting both the public and policymakers. The code presents 17 evidence-based recommendations for cancer prevention that are not only effective but also feasible and implementable within Latin American contexts.
7 months ago
EDUARDO CAZAP
Professor Yin describes his research involving the protein kinase PAK1, which functions as a "master controller of T-cell immunity." PAK1 acts as a promoter of CD8+ T-cell exhaustion and contributes to decreased tumor immunity, making this molecule a potential target for cancer immunotherapy. His research also explores cancer detection through metabolomics combined with artificial intelligence as a screening tool for lung and pancreatic cancers.
7 months ago
YUXIN YIN
Pharmacogenomics is an emerging field of genetic testing that identifies individuals who metabolize commonly used drugs—including many cancer therapies—either too rapidly (resulting in reduced efficacy) or too slowly (leading to drug toxicity). Adverse drug reactions are the fourth leading cause of death in the United States, with oncology drugs being a major driver of drug-related toxicity. A Chinese National Genomics Pilot Study involving over 6,000 cancer patients demonstrated that dose adjustments based on individual patient genomes significantly reduced drug toxicity-related hospitalizations and decreased overall hospital costs.
7 months ago
BERNARD ESQUIVAR