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City of Hope Intensive Course in Genomic Cancer Risk Assessment

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ISOPT INAUGURAL CONGRESS - JUNE 2025

Genetics, Immunology & Precision Medicine

Jun 21, 2026
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Immune Regulation and Cancer Immune Therapy 19:47

Immune Regulation and Cancer Immune Therapy

Yuxin Yin

Professor Yin describes his research involving the protein kinase PAK1, which functions as a "master controller of T-cell immunity." PAK1 acts as a promoter of CD8+ T-cell exhaustion and con...

Professor Yin describes his research involving the protein kinase PAK1, which functions as a "master controller of T-cell immunity." PAK1 acts as a promoter of CD8+ T-cell exhaustion and contributes to decreased tumor immunity, making this molecule a potential target for cancer immunotherapy. His research also explores cancer detection through metabolomics combined with artificial intelligence as a screening tool for lung and pancreatic cancers.