Accepting applications until August 1

City of Hope Intensive Course in Genomic Cancer Risk Assessment

Accepting applications until August 1

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ISOPT INAUGURAL CONGRESS - JUNE 2025

GI / Colorectal / Pancreatic Cancer

Jun 21, 2025
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Overcoming immunotherapy resistance in treating GI cancer 18:04

Overcoming immunotherapy resistance in treating GI cancer

Rui-Hua Xu

Gastroesophageal and colorectal cancers are a major life-threatening disease and often present at advanced stages. Discussions about selecting high-immunogenecity subtypes (such as MSI hi; h...

Gastroesophageal and colorectal cancers are a major life-threatening disease and often present at advanced stages. Discussions about selecting high-immunogenecity subtypes (such as MSI hi; high TMB) to optimize chemoimmunotherapy combinations and facilitate organ-sparing operations, and to propose new strategies for improving immunotherapy efficiency in GI cancers by reversing immunotherapy resistance with drugs that induce immunogenic tumor cell death and to modulate the immune microenvironment.