Articles

Early-Onset Cancers Are on the Rise. Knowing Your Family History Is Crucial

Cara Anthony, Blake Farmer. KFF Health News / Nashville Public Radio. 2026 Jun 16.

More than a dozen cancers are now rising among U.S. adults under 50, with colorectal and breast cancers increasing the most; colorectal cancer is now the deadliest cancer for Americans ages 18 to 49. No single cause has been identified, but contributing factors likely include obesity, heavy alcohol use, environmental e... Read More

20 Jun, 2026

A new screening study built for people who carry a cancer gene

PATROL, a multicenter prospective study published in BJU International on June 9, screens men who carry an inherited pathogenic variant in a prostate cancer risk gene (BRCA2, BRCA1, ATM, CHEK2, HOXB13, and the Lynch syndrome genes) on a different clock than the general population. Carriers start at age 40, and the thre... Read More

20 Jun, 2026

The Number-1 Sign of Colon Cancer Doctors Say You Shouldn't Ignore

Alyssa Sybertz. Prevention (via AOL). 2026 Jun 18

Colon cancer is highly treatable when caught early, with a five-year survival rate of roughly 90% for localized, early-stage disease, yet it is often difficult to diagnose because it can develop without symptoms or mimic benign conditions like hemorrhoids, infection, or constipation. Gastroenterologists interviewed ide... Read More

20 Jun, 2026

G7 Leaders' Call on the Fight Against Cancer

OncoDaily. 2026 Jun 18

On June 17, 2026, the leaders of the G7—joined by Brazil, Egypt, India, Kenya, and the Republic of Korea—issued a joint call to accelerate the global fight against cancer, a disease that kills nearly 10 million people a year and whose incidence is projected to rise 80% by 2050. The declaration commits signatories to de... Read More

20 Jun, 2026

Age-Based Screening for Lung Cancer Surveillance in the US

Hee Chul Yang, Austin Chang, Maxime Visa, et al. JAMA Netw Open. 2025 Nov 3;8(11):e2546222

Lung cancer is increasingly diagnosed in never-smokers, suggesting that the current US Preventive Services Task Force (USPSTF) screening criteria using low-dose computed tomography exclude many at-risk individuals, thus raising concerns about their effectiveness and equity. Patients with lung cancer diagnosed from ... Read More

13 May, 2026

Global esophageal cancer epidemiology in 2022 and predictions for 2050: A comprehensive analysis and projections based on GLOBOCAN data

Ling Qi , Mengfei Sun, Weixin Liu, et al. Chin Med J (Engl). 2024 Dec 20;137(24):3108-3116

The aim of this study is to analyze the current burden of esophageal cancer in 185 countries in 2022 and to project the trends up to the year 2050. In 2022, an estimated 511,054 people were diagnosed with esophageal cancer globally, and 445,391 died from the disease. The global ASIR and ASMR for esophageal cancer ... Read More

13 May, 2026

The gut microbiome is associated with disease-free survival in stage I-III colorectal cancer patients

Doratha A Byrd, Victoria Damerell, Maria F Gomez Morales, et al. Int J Cancer. 2025 Jul 1;157(1):64-73

Colorectal cancer (CRC) is the second overall leading cause of cancer death in the United States, with recurrence being a frequent cause of mortality. The gut microbiome, reflected in fecal samples, is likely mechanistically linked to CRC progression and may serve as a non-invasive biomarker. Accordingly, we levera... Read More

13 May, 2026

Canadian Recommendations for Germline Genetic Testing of Patients with Breast Cancer: A Call to Action

Evan Weber, Carlos A Carmona-Gonzalez, Melanie Boucher, et al. Curr Oncol. 2025 May 22;32(6):290

Pathogenic variants in breast cancer predisposition genes are associated with poor clinical outcomes but also offer an opportunity for more individualized therapeutic pathways. Given increasing knowledge, improvements in germline genetic testing efficiency, and the availability of novel systemic targeted treatment... Read More

13 May, 2026

Universal Genetic Testing for Newly Diagnosed Invasive Breast Cancer

Zoulikha Rezoug , Stephanie P Totten, David Szlachtycz, et al. JAMA Netw Open. 2024 Sep 3;7(9):e2431427

Between 5% and 10% of breast cancer cases are associated with an inherited germline pathogenic or likely pathogenic variant (GPV) in a breast cancer susceptibility gene (BCSG), which could alter local and systemic therapy recommendations. Of 1017 referred patients, 805 were eligible and offered genetic counseling a... Read More

13 May, 2026

Genetic predisposition to persistent fatigue after a diagnosis of colorectal cancer

Elham Kazemian , Qianxing Mo , Marco Matejcic, et al. J Natl Cancer Inst. 2025 Dec 1;117(12):2513-2525

Cancer-related fatigue (fatigue) is a common and persistent symptom after cancer treatment, yet the role of genetic susceptibility remains unclear. We used data from a prospective cohort study called the ColoCare Study, conducted over 5 US sites and Germany. Fatigue was assessed at 5 time points using the European ... Read More

13 May, 2026