Accepting applications until August 1

City of Hope Intensive Course in Genomic Cancer Risk Assessment

Accepting applications until August 1

Early-Onset Gastrointestinal Cancers: A Review

Thejus Jayakrishnan, Kimmie Ng. JAMA. 2025 Oct 21;334(15):1373-1385

Early-onset gastrointestinal (GI) cancer is typically defined as GI cancer diagnosed in individuals younger than 50 years. The incidence of early-onset GI cancer is rising globally, and early-onset GI cancers represent the most ra... Read More

The global burden and trends analysis of early-onset colorectal cancer attributable to dietary risk factors in 204 countries and territories, 1990-2019: a secondary analysis for the global burden of disease study 2019

Jiao Su, Yuanhao Liang, Xiaofeng He, et al. Front Nutr. 2024 May 31:11:1384352

Rising trends in early-onset colorectal cancer (CRC) burden have been observed, but the distribution and temporal patterns of early-onset CRC attributable to dietary risks remain unclear. This study aimed to estimate the burden of... Read More

Increase of early-onset colorectal cancer: a cohort effect

Laura Downham, Mathieu Laversanne , Sandra Perdomo, et al JNCI: Journal of the National Cancer Institute, 2025, 00(00), 1–6

Increasing incidence rates of early-onset colorectal cancer (ie, <50years of age) have been reported across multiple countries. We investigated long-term cancer incidence data from 1995 or earlier from Australia, Canada, Englan... Read More

Age-specific trends in colorectal, appendiceal, and anal tumor incidence by histological subtype in Australia from 1990 to 2020: a population-based time-series analysis

Aaron L. Meyers, James G. Dowty, Khalid Mahmood, et al. The Lancet Regional Health – Western Pacific 2025;64

Early-onset bowel cancer incidence (age <50 years) has increased worldwide. Combining all malignant tumor histologies, early-onset incidence rose 5–9% annually, yielding 4072 excess cases (1⋅5 per 100,000 person-years; 15% appe... Read More