Thejus Jayakrishnan, Kimmie Ng. JAMA. 2025 Oct 21;334(15):1373-1385
Early-onset gastrointestinal (GI) cancer is typically defined as GI cancer diagnosed in individuals younger than 50 years. The incidence of early-onset GI cancer is rising globally, and early-onset GI cancers represent the most ra...
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Jian Li, Xiaohong Kuang. Public Health 237 (2024) 336–343
This study aimed to assess the disease burden of cancer in young adults globally and the changes between 2012 and 2022. In young adults, 47.22 % of new cases were breast, thyroid and cervical cancer, while the leading causes of ca...
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Jiao Su, Yuanhao Liang, Xiaofeng He, et al. Front Nutr. 2024 May 31:11:1384352
Rising trends in early-onset colorectal cancer (CRC) burden have been observed, but the distribution and temporal patterns of early-onset CRC attributable to dietary risks remain unclear. This study aimed to estimate the burden of...
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Laura Downham, Mathieu Laversanne , Sandra Perdomo, et al JNCI: Journal of the National Cancer Institute, 2025, 00(00), 1–6
Increasing incidence rates of early-onset colorectal cancer (ie, <50years of age) have been reported across multiple countries. We investigated long-term cancer incidence data from 1995 or earlier from Australia, Canada, Englan...
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Hyuna Sung, Rebecca L Siegel, Mathieu Laversanne, et al. Lancet Oncol 2025; 26: 51–63. 2025
Previous studies have shown that colorectal cancer incidence is increasing among younger adults (aged <50 years) in multiple high-income western countries in contrast with stabilizing or decreasing trends in incidence in older...
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Yuzhou Cai, Fangyi Dai, Ying Ye, et al. Sci Rep. 2025 Mar 18;15(1):9347
Breast cancer is the most prevalent malignant disease among women and affects women of reproductive age (15-49 years) across the globe. This study examines patterns and trends in the epidemiology of breast cancer in women of repro...
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Wenmei 1, Kaijian Zhou 2, Liang He 3, et al. Endocrinol Metab (Seoul). 2026 Jan 5
Early-onset cancers (diagnosed in individuals under 50 years of age) are increasingly contributing to the global cancer burden. Among the known contributors, specific metabolic risk factors-namely high body mass index (BMI) and hi...
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Wenxin Yan, Min Liu, Wenzhan Jing et al. Exp Hematol Oncol. 2025 Mar 17;14(1):38
The global cancer burden is rising, with early-onset cancers becoming more prevalent. We aimed to investigate the burden, trend and population disparity in 33 early-onset cancers from 2012 to 2021. In 2021, there were 2.65 mi...
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Rupayan Kundu, Ankush Mukhopadhyay, Niladri Kal, et al .JCO Glob Oncol 12, e2500170(2026). Volume 12
Early-onset cancer (EOC), defined as cancer occurring in individuals age 15-49 years, represents a growing global health burden. In 2021, there were approximately 23.6 million new EOC cases and 0.99 million deaths globally....
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Emma Ruiz-Moreno, Javier García-Péreza,Virginia Lope. Gaceta Sanitaria 40 (2026) 102565
PreveCan is a useful tool to inform Spanish-speaking users on lifestyle changes to reduce cancer risk by assessing adherence to WCRF/AICR cancer prevention guidelines. The app was developed using a user-centred design approach inv...
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Eva Blondeaux1, Amir Sonnenblick, Elisa Agostinetto et al. Lancet Oncol. 2025 26(6):759-770
We investigated the association between risk-reducing mastectomy (RRM) or risk-reducing salpingo-oophorectomy (RRSO), or both procedures, with survival outcomes in a large global cohort of young BRCA carriers with previous breast...
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