Xin Yang, Juliet A Usher-Smith, Kristina M Blackmore, et al.
Risk-based breast cancer (BC) screening can provide tailored recommendations based on individual risk. We estimated 10-year BC risks in 3753 women aged 40-70 with no cancer history. The primary endpoint was risk reclassification,...
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Advaith N Rao, Adithya Sathya Narayana, Vinay C Bellur, et al.
Young onset colorectal cancer (YOCRC) is a significant clinical problem in India. This study aims to compare the clinical and pathological characteristics of colorectal cancer in younger (< 45 years) and older (≥ 45 years) pati...
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S. Daniel Haldar, Amanda Huff, Hejia Henry, et al.
Pancreatic ductal adenocarcinoma (PDAC) arises from precursor lesions over a decade-plus, offering a window for interception in high-risk individuals, but current surveillance detects a minority of precursors. Mutant KRAS (mKRAS)...
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Muhammad Babar Khawar, Muhammad Faisal Maqbool, Ali Afzal, et al.
Colorectal cancer (CRC) is the second leading cause of cancer deaths worldwide. In South Asia, demographic shifts, dietary changes, and healthcare disparities are influencing CRC trends. This study evaluated temporal patterns, pro...
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Karim Abdel Wahab, Ahmed Hassan, Ahmed Morsi, et al.
In Egypt, there were 150,578 new cancer cases and 95,275 cancer deaths in 2022, indicating a substantial burden on patients and the healthcare system. In 2019, Egypt had a total of 45,114 deaths, from liver, lung, breast, cervical...
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Leonor Vasconcelos de Matos, Margarida Borges, Ana Teresa Oliveira, et al.
This study aimed to characterize the employment status and work-related conditions of patients with advanced breast cancer (ABC) in Portugal and quantify the productivity costs of premature abandonment of the work market while eva...
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Low-fiber diets are a known risk factor for colorectal cancer (CRC). This study assesses the global, regional, and national burden of CRC due to low-fiber diets from 1990 to 2021. The analysis showed significant disparities in CRC...
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Nobuhiro Nakazawa, Satoko Ugai, Atsushi Kondo, et al.
The incidence of early-onset cancers, commonly defined as cancers diagnosed before age 50 years, has been increasing globally over recent decades. In particular, the incidence of several early-onset digestive system cancers, inclu...
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Ilektra Kyrochristou, Fotios Fousekis, Gerasimia D Kyrochristou, et al.
As This systematic review aims to present the available data on the role of gut microbiota in colorectal cancer diagnosis, prognosis, and treatment response. Thirty-six studies met the inclusion criteria, encompassing case-control...
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The rising incidence of early-onset colorectal cancer (CRC) has prompted debate over lowering screening initiation age. Our study aimed to evaluate screening yield of FIT-based CRC screening between 45-49 and 50-54 years. Conducte...
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Durgesh Wankhede Mary Jose Urruchua Rodriguez, Franziska Teich, et al.
The incidence of early-onset colorectal cancer (EOCRC), diagnosed in individuals under 50 years, is rising across Europe, presenting a growing public health challenge distinct from later-onset disease. Clinically, EOCRC in Europe...
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The incidence of early-onset colorectal cancer (EO-CRC; age <50 years) has been increasing worldwide. A total of 1,148 CRC patients were retrospectively analyzed and categorized into EO-CRC (n = 247) and LO-CRC (n = 901) groups...
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