Early-onset colorectal cancer (EOCRC) is increasing worldwide and exhibits clinical heterogeneity. Patients younger than 40 years may constitute a biologically distinct subgroup within EOCRC. A total of 264 patients were included...
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Advaith N Rao, Adithya Sathya Narayana, Vinay C Bellur, et al.
Young onset colorectal cancer (YOCRC) is a significant clinical problem in India. This study aims to compare the clinical and pathological characteristics of colorectal cancer in younger (< 45 years) and older (≥ 45 years) pati...
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Nobuhiro Nakazawa, Satoko Ugai, Atsushi Kondo, et al.
The incidence of early-onset cancers, commonly defined as cancers diagnosed before age 50 years, has been increasing globally over recent decades. In particular, the incidence of several early-onset digestive system cancers, inclu...
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Durgesh Wankhede Mary Jose Urruchua Rodriguez, Franziska Teich, et al.
The incidence of early-onset colorectal cancer (EOCRC), diagnosed in individuals under 50 years, is rising across Europe, presenting a growing public health challenge distinct from later-onset disease. Clinically, EOCRC in Europe...
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The incidence of early-onset colorectal cancer (EO-CRC; age <50 years) has been increasing worldwide. A total of 1,148 CRC patients were retrospectively analyzed and categorized into EO-CRC (n = 247) and LO-CRC (n = 901) groups...
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The rising incidence of early-onset colorectal cancer (CRC) has prompted debate over lowering screening initiation age. Our study aimed to evaluate screening yield of FIT-based CRC screening between 45-49 and 50-54 years. Conducte...
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Ilektra Kyrochristou, Fotios Fousekis, Gerasimia D Kyrochristou, et al.
As This systematic review aims to present the available data on the role of gut microbiota in colorectal cancer diagnosis, prognosis, and treatment response. Thirty-six studies met the inclusion criteria, encompassing case-control...
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Low-fiber diets are a known risk factor for colorectal cancer (CRC). This study assesses the global, regional, and national burden of CRC due to low-fiber diets from 1990 to 2021. The analysis showed significant disparities in CRC...
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Muhammad Babar Khawar, Muhammad Faisal Maqbool, Ali Afzal, et al.
Colorectal cancer (CRC) is the second leading cause of cancer deaths worldwide. In South Asia, demographic shifts, dietary changes, and healthcare disparities are influencing CRC trends. This study evaluated temporal patterns, pro...
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Sven Voigtländer, Hiltraud Kajüter, Ina Wellmann, et al.
Motivated by studies on early-onset colorectal cancer (EO CRC, below 50 years) from the United States (US) and elsewhere, this study aimed to provide national incidence trends of EO CRC for Germany. For comparison, US cancer regis...
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Incidence of early-onset cancer is rising globally in recent generations, which underscores the need to elucidate the influence of emerging generational risk factors. Systemic and organ-specific aging reflects the cumulative impac...
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The incidence of early-onset colorectal cancer (EOCRC) is increasing worldwide, and CRC survivors may have an elevated risk of second primary cancer (SPC). This retrospective study analyzed 13,302 CRC patients diagnosed between 20...
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