The increasing incidence of early-onset colorectal cancer (age <50 years; EOCRC) shows a dramatic growing trend globally, while late-onset colorectal cancer (LOCRC) is gradually decreasing. Between Jan 1 and Dec 31, 2024, 17 13...
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Thejus Jayakrishnan, Kimmie Ng. JAMA. 2025 Oct 21;334(15):1373-1385
Early-onset gastrointestinal (GI) cancer is typically defined as GI cancer diagnosed in individuals younger than 50 years. The incidence of early-onset GI cancer is rising globally, and early-onset GI cancers represent the most ra...
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Jiao Su, Yuanhao Liang, Xiaofeng He, et al. Front Nutr. 2024 May 31:11:1384352
Rising trends in early-onset colorectal cancer (CRC) burden have been observed, but the distribution and temporal patterns of early-onset CRC attributable to dietary risks remain unclear. This study aimed to estimate the burden of...
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Laura Downham, Mathieu Laversanne , Sandra Perdomo, et al JNCI: Journal of the National Cancer Institute, 2025, 00(00), 1–6
Increasing incidence rates of early-onset colorectal cancer (ie, <50years of age) have been reported across multiple countries. We investigated long-term cancer incidence data from 1995 or earlier from Australia, Canada, Englan...
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Hyuna Sung, Rebecca L Siegel, Mathieu Laversanne, et al. Lancet Oncol 2025; 26: 51–63. 2025
Previous studies have shown that colorectal cancer incidence is increasing among younger adults (aged <50 years) in multiple high-income western countries in contrast with stabilizing or decreasing trends in incidence in older...
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Wenmei 1, Kaijian Zhou 2, Liang He 3, et al. Endocrinol Metab (Seoul). 2026 Jan 5
Early-onset cancers (diagnosed in individuals under 50 years of age) are increasingly contributing to the global cancer burden. Among the known contributors, specific metabolic risk factors-namely high body mass index (BMI) and hi...
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Farhad Islami MD, Emily C. Marlow, Blake Thomson, et al. CA Cancer J Clin. 2024;74:405–432
The authors estimated the proportion and number of invasive cancer cases (excluding nonmelanoma skin cancers) and deaths, overall and for 30 cancer types among adults who were aged 30 years and older in 2019 in the United States,...
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Katrina A. B. Goddard; Eric J. Feuer; Jeanne S. Mandelblatt; et al. JAMA Oncol. 2025;11(2):162-167.
The contributions of different interventions across the cancer control continuum was evaluated with primary prevention via smoking reduction (lung), screening for interception (cervix and colorectal) or early detection (breast, ce...
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Silvia Mignozzi, Claudia Santucci, Fabio Levi, et al. Eur J Cancer Prev. 2026 Mar 1;35(2):97-107.
We provided cancer mortality rate estimates for the year 2025 in six Latin American countries (Argentina, Brazil, Chile, Colombia, Cuba, and Mexico), focusing on prostate cancer. We extracted mortality data for all cancers combine...
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Tania Alfaro, Kevin Martinez-Folgar, Dalia Stern, et al. Lancet Glob Health. 2025 Feb;13(2):e268-e276.
Understanding between-city variations in cancer mortality is crucial to inform national and subnational cancer prevention strategies. As part of the Salud Urbana en América Latina (SALURBAL) project, we aimed to describe the varia...
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Yujie Wu, Siyi He, Mengdi Cao,et al. Chin Med J (Engl) 2024 Dec 20;137(24):3093-3100
https://doi.org/10.1016/j.jncc.2024.06.005 In 2024, there are an estimated 3,246,625 and 2,510,597 new cancer cases and 1,699,066 and 640,038 cancer deaths in China and the US, respectively. The highest estimated cancer cases are...
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