Ehsan Ullah, Hikmat Abdel-Razeq, Sana Bentebbal, et al.
The Middle East and North African (MENA) region broadly mirrors global cancer trends, with breast cancer remaining the most common cancer among women. However, regional differences in germline BRCA1/2 mutation prevalence suggest t...
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Xin Yang, Juliet A Usher-Smith, Kristina M Blackmore, et al.
Risk-based breast cancer (BC) screening can provide tailored recommendations based on individual risk. We estimated 10-year BC risks in 3753 women aged 40-70 with no cancer history. The primary endpoint was risk reclassification,...
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Yiwey Shieh, Rachel S. Heise, Lisa Madlensky et al.
Risk-based breast cancer screening has emerged as a viable alternative to annual mammography. To guide implementation, knowledge is needed on the contribution of testing for pathogenic variants (PVs) beyond clinical risk factors a...
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To investigate the relationship between genetic risk and the four main lifestyle factors in HNC development, we used data from 356,627 participants in the UK Biobank. Genetic risk was measured using a polygenic risk score (PRS), c...
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S. Ogino and T. Ugai. Annals of Oncol;.35(12) 1071-1073. 2024
The incidence of early-onset cancer (EOC) diagnosed in individuals under the age of 50 has been increasing worldwide, which may be just the tip of the iceberg of larger emerging issues, including the rise of various chronic diseas...
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Laura J. Esserman; Allison S. Fiscalini; Arash Naeim. JAMA Published online December 12, 2025
Individual breast cancer risk can guide screening initiation, frequency, use of supplemental imaging, and preventive measures to improve breast cancer screening by shifting resources from low-risk women to high-risk women. To dete...
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