Daniel Redondo-Sánchez 1, Dafina Petrova 2, Jàmnica Bigorra 3, et al.
This collaborative study within the Spanish Network of Cancer Registries (REDECAN) aimed to examine cancer incidence trends in young adults in Spain. A total of 153,599 new cancer cases (58% in women) were diagnosed during the stu...
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Incidence of early-onset cancer is rising globally in recent generations, which underscores the need to elucidate the influence of emerging generational risk factors. Systemic and organ-specific aging reflects the cumulative impac...
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Early-onset colorectal cancer (EOCRC) is increasing worldwide and exhibits clinical heterogeneity. Patients younger than 40 years may constitute a biologically distinct subgroup within EOCRC. A total of 264 patients were included...
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Karim Abdel Wahab, Ahmed Hassan, Ahmed Morsi, et al.
In Egypt, there were 150,578 new cancer cases and 95,275 cancer deaths in 2022, indicating a substantial burden on patients and the healthcare system. In 2019, Egypt had a total of 45,114 deaths, from liver, lung, breast, cervical...
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Early-onset lung cancer, commonly defined as disease diagnosed at or before 50 years of age, represents a growing but insufficiently characterized subset of lung cancer in clinical practice. However, much of the evidence informing...
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Marianna De Camargo Cancela, Jonas Eduardo Monteiro Dos Santos, Leonardo Borges Lopes de Souza, et al.
About half of cancer deaths in Brazil occur among individuals of working-age (under 65 years for men, under 60 for women), resulting in a substantial economic impact for the country. Between 2001 and 2030, a total of 2.3 million p...
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Yek-Ching Kong, Jean Niyigaba, Phuong Bich Tran, et al.
Cancer is among the most important causes of premature deaths globally. We estimated the value of paid and unpaid productivity losses due to premature mortality in 2022 from all cancers worldwide.Years of productive life lost were...
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On June 17, 2026, the leaders of the G7—joined by Brazil, Egypt, India, Kenya, and the Republic of Korea—issued a joint call to accelerate the global fight against cancer, a disease that kills nearly 10 million people a year and w...
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Hee Chul Yang, Austin Chang, Maxime Visa, et al. JAMA Netw Open. 2025 Nov 3;8(11):e2546222
Lung cancer is increasingly diagnosed in never-smokers, suggesting that the current US Preventive Services Task Force (USPSTF) screening criteria using low-dose computed tomography exclude many at-risk individuals, thus raising co...
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Agnes Brandtmüller, Anne Meiwald, Edward Oliver, et al. J Cancer Policy. 2024 Dec:42:100499
Cancer caused an estimated 2.2 million deaths across Europe in 2020. This analysis estimated the cost of lost productivity due to premature deaths associated with lung, breast and melanoma cancer and investigated the temporal tren...
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Sibylle Loibl, Yeon Hee Park, Zhiming Shao, et al. N Engl J Med. 2026 Feb 26;394(9):845-857
A total of 1635 patients were randomly assigned (in a 1:1 ratio) to receive T-DXd (818 patients) or T-DM1 (817 patients). Invasive-disease events or deaths were reported in 51 patients (6.2%) in the T-DXd group and 102 patients (1...
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Yibei Li, Danqi Huang, Jingyi Liu, et al. J Natl Cancer Cent. 2026 Feb 11;6(2):149-158
Early-onset cancer is a significant public health threat in females, yet comprehensive data on its global burden and temporal trends remain limited. This study analyzed the incidence, mortality, and disability-adjusted life years...
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