There has been a concerning 79.1% global rise in incidence between 1990 and 2019 of early onset cancer (EOC), defined as cancers diagnosed under age 50. EOC diagnoses now account for 12% of all cancer diagnoses. The largest increa...
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Daniel Redondo-Sánchez 1, Dafina Petrova 2, Jàmnica Bigorra 3, et al.
This collaborative study within the Spanish Network of Cancer Registries (REDECAN) aimed to examine cancer incidence trends in young adults in Spain. A total of 153,599 new cancer cases (58% in women) were diagnosed during the stu...
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S. Ogino and T. Ugai. Annals of Oncol;.35(12) 1071-1073. 2024
The incidence of early-onset cancer (EOC) diagnosed in individuals under the age of 50 has been increasing worldwide, which may be just the tip of the iceberg of larger emerging issues, including the rise of various chronic diseas...
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In recent years, the incidence of early-onset cancers among individuals under 50 years of age has been on the rise. From 1990 to 2021, the incidence rate of all early-onset cancers in China increased by 150.72 per 100,000, while t...
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Early-onset cancer (EOC), occurring in individuals aged 15-49 years, is a growing global health concern. High body mass index (BMI) is an established modifiable risk factor contributing to cancer morbidity and mortality. In 2021,...
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Hao Dai; Yongqiu Li; Yao An Lee; et al. JAMA Oncol. Published online August 21, 2025
Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are widely prescribed for glycemic control in type 2 diabetes and have recently gained popularity for weight management. We compared the incidence of 14 cancers among adults wit...
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Lindsey Wang, Rong Xu, David C Kaelber et al. JAMA Netw Open 2024;7;(7):e2421305
Thirteen human malignant neoplasms have been identified as obesity-associated cancers (OACs), ie, the presence of excess body fat is associated with increased risk of developing cancer and worse prognosis in patients with these sp...
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Darren R. Brenner; Yibing Ruan; Chantelle Carbonell. JAMA Network Open. 2025;8(9):e2530904
Excess body size has emerged as an impactful component of population-level cancer risk. Current data suggest that at least 13 cancer sites are convincingly associated with excess body size, most often characterized by a body mass...
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Hongmei Zeng, Rongshou Zheng, Kexin Sun et al. J Natl Cancer Cent. 2024 Jun 22;4(3):203-213
A milestone goal of the Healthy China Program (2019-2030) is to achieve 5-year cancer survival at 43.3% for all cancers combined by 2022. To assess the progress towards this target, we analyzed the updated survival for all cancers...
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