Ning Liao, Nanqiu Liu, Guochun Zhang, et al. European Journal of Surgical Oncology published online January 2026
This pilot study evaluated the feasibility of a novel technique combining ultrasound-guided and indocyanine green (ICG) intra-tumoral injection with robot-assisted surgery to enable accurate local excision. A novel surgical techni...
Read More
Matteo Lambertini , Eva Blondeaux , Loredana M Tomasello.et al. J Clin Oncol. 2025 May 10;43(14):1706-1719
To investigate the clinical behavior of breast cancer in young BRCA carriers according to the specific BRCA gene (BRCA1 v BRCA2) and the association of the timing of genetic testing (before v at diagnosis) with prognosis. Compared...
Read More
Xia Wei , Lea Mansour , Samuel Oxley, et al. JAMA Oncol. 2025 Jul 24;11(9):1072-1082.
Expanding access to genetic testing and availability of validated breast cancer (BC) risk prediction models are increasingly identifying women at elevated BC risk who do not carry high-penetrance BRCA1/BRCA2/PALB2 pathogenic varia...
Read More
Eva Blondeaux 1, Amir Sonnenblick 2, Elisa Agostinetto . Lancet Oncol. 2025 Jun;26(6):759-770
The BRCA BCY Collaboration is an international, hospital-based, retrospective cohort study, conducted at 109 centers in five continents, including women harboring germline BRCA1, BRCA2, or both, pathogenic or likely pathogenic var...
Read More
Puneet Singh, Doreen M Agnese, Miral Amin, et al. Ann Surg Oncol. 2025 Feb;32(2):899-911.
Bilateral risk-reducing mastectomy (BRRM) is the surgical removal of both breasts to reduce the risk of cancer. In this Society of Surgical Oncology position statement, we review the literature addressing the indications, outcomes...
Read More
Henry M Kuerer 1, Vicente Valero 2, Benjamin D Smith 3, et al. JAMA Oncol. 2025 May 1;11(5):529-534
Neoadjuvant systemic therapy (NST) has been associated with pathologic complete response (pCR) in up to 60% of breast cancers (BCs). The findings of this trial question the necessity of surgery. To report preplanned 5-year efficac...
Read More
Yuzhou Cai , Ying Ye , Jingxian Qian. Public Health. 2025 May:242:340-351
This study aimed to assess global, regional, and national trends in breast cancer burden attributable to high body mass index (BMI) from 1990 to 2021 and provide projections up to 2036 using data from the Global Burden of Disease...
Read More
Early-onset cancer (EOC), occurring in individuals aged 15-49 years, is a growing global health concern. High body mass index (BMI) is an established modifiable risk factor contributing to cancer morbidity and mortality. In 2021,...
Read More
Xiaoru Feng, Ruoqian Li, and Hang Yi. Obesity. 2025 Mar;33(3):567-577
The objective of this study was to estimate cancer burden attributable to excess body weight (EBW) and identify its main source. The incidence of 11 EBW-related cancers has increased from 1990 to 2021. Later-born cohorts and older...
Read More
Lindsey Wang, Rong Xu, David C Kaelber et al. JAMA Netw Open 2024;7;(7):e2421305
Thirteen human malignant neoplasms have been identified as obesity-associated cancers (OACs), ie, the presence of excess body fat is associated with increased risk of developing cancer and worse prognosis in patients with these sp...
Read More
Darren R. Brenner; Yibing Ruan; Chantelle Carbonell. JAMA Network Open. 2025;8(9):e2530904
Excess body size has emerged as an impactful component of population-level cancer risk. Current data suggest that at least 13 cancer sites are convincingly associated with excess body size, most often characterized by a body mass...
Read More
Laura J. Esserman; Allison S. Fiscalini; Arash Naeim. JAMA Published online December 12, 2025
Individual breast cancer risk can guide screening initiation, frequency, use of supplemental imaging, and preventive measures to improve breast cancer screening by shifting resources from low-risk women to high-risk women. To dete...
Read More