Nobuhiro Nakazawa, Satoko Ugai, Atsushi Kondo, et al.
The incidence of early-onset cancers, commonly defined as cancers diagnosed before age 50 years, has been increasing globally over recent decades. In particular, the incidence of several early-onset digestive system cancers, inclu...
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The rising incidence of early-onset colorectal cancer (CRC) has prompted debate over lowering screening initiation age. Our study aimed to evaluate screening yield of FIT-based CRC screening between 45-49 and 50-54 years. Conducte...
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Marianna De Camargo Cancela, Jonas Eduardo Monteiro Dos Santos, Leonardo Borges Lopes de Souza, et al.
About half of cancer deaths in Brazil occur among individuals of working-age (under 65 years for men, under 60 for women), resulting in a substantial economic impact for the country. Between 2001 and 2030, a total of 2.3 million p...
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Early-onset colorectal cancer (EOCRC), defined as colorectal cancer diagnosed before 50 years of age, has increased markedly over the past decades, especially in high-income settings. In parallel, obesity and related metabolic dis...
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This systematic review and meta-analysis aimed to assess the global prevalence and determinants of financial toxicity in colorectal cancer (CRC) patients. 65 studies met inclusion criteria. The pooled prevalence of objective finan...
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Cara Anthony, Blake Farmer. KFF Health News / Nashville Public Radio. 2026 Jun 16.
More than a dozen cancers are now rising among U.S. adults under 50, with colorectal and breast cancers increasing the most; colorectal cancer is now the deadliest cancer for Americans ages 18 to 49. No single cause has been ident...
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Colon cancer is highly treatable when caught early, with a five-year survival rate of roughly 90% for localized, early-stage disease, yet it is often difficult to diagnose because it can develop without symptoms or mimic benign co...
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Hee Chul Yang, Austin Chang, Maxime Visa, et al. JAMA Netw Open. 2025 Nov 3;8(11):e2546222
Lung cancer is increasingly diagnosed in never-smokers, suggesting that the current US Preventive Services Task Force (USPSTF) screening criteria using low-dose computed tomography exclude many at-risk individuals, thus raising co...
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Doratha A Byrd, Victoria Damerell, Maria F Gomez Morales, et al. Int J Cancer. 2025 Jul 1;157(1):64-73
Colorectal cancer (CRC) is the second overall leading cause of cancer death in the United States, with recurrence being a frequent cause of mortality. The gut microbiome, reflected in fecal samples, is likely mechanistically linke...
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Elham Kazemian , Qianxing Mo , Marco Matejcic, et al. J Natl Cancer Inst. 2025 Dec 1;117(12):2513-2525
Cancer-related fatigue (fatigue) is a common and persistent symptom after cancer treatment, yet the role of genetic susceptibility remains unclear. We used data from a prospective cohort study called the ColoCare Study, conducted...
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Karely M van Thiel Berghuijs, Heydon K Kaddas, et al. J Cancer Surviv. 2024 Jun;18(3):1075-1084
Employment and financial hardships are common issues for working-age colorectal cancer patients. We surveyed colorectal cancer survivors to investigate employment, insurance, and financial outcomes by age at diagnosis. There were...
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Pasquale Marino, Mariangela Mininni, Giovanni Deiana, et al. Nutrients. 2024 Mar 11;16(6):800
Cancer has become a serious problem worldwide, as it represents the main cause of death, and its incidence has increased over the years. A potential strategy to counter the growing spread of various forms of cancer is the adoption...
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